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Cell differentiation is how generic embryonic cells become specialized cells. This occurs through a process called gene expression . Gene expression is the specific combination of genes that are turned on or off ( expressed or repressed ), and this is what dictates how a cell functions. Gene expression occurs because of certain signals in your body, both inside and outside of your cells.

Cell differentiation occurs during multiple stages of development. During cell differentiation, the cell size and shape changes dramatically, as does its ability to respond to signaling molecules . Signaling molecules are molecules that bring messages to cells that help the cell know which activities and processes to perform.

Signaling molecules carry a message to a cell receptor , which interprets the message through a signal transduction pathway . This pathway translates the message into something that the cell can recognize and understand, and this is what tells a cell how to function.

As your cells develop and differentiate, they become quite different in structure and function. Once this differentiation begins, a cell is bound to that fate and must continue down its path of differentiation. Each type of cell that develops creates tissue-specific proteins , which are only found in that cell type and are what give the cell its unique structure and function.

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Cells need to have different structures because they have different functions. A sperm cell has a function that is very different from a skin cell or a liver cell. If a sperm cell were not shaped the way it is, it would have a very difficult time swimming to an egg to fertilize it.

Certain cells in your eyes, known as and , are designed to receive light and perceive objects. They are shaped the way they are because this allows them to do their job most efficiently. If they were shaped any other way, they would not be able to function properly, and you would not be able to see very well.

Your body has an enormous amount of differentiated cells, but your cells are also different from the cells of other organisms, such as plants, insects, bacteria, fish, mammals and birds. Cellular differentiation allows for this great diversity of life on Earth and makes us each uniquely suited to our environmental conditions.

Lesson Summary

Let's review. is the process of cells developing and specializing from generic embryonic cells. Cell differentiation creates all of the different structures in your body, like muscles, bones and organs. Cell differentiation also produces the vast number of organisms on Earth and allows for many different cell structures to exist and function both properly and efficiently.

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FTCE Biology Grades 6-12 (002): Practice Study Guide

Summary:
Prepare to take the FTCE Biology 6-12 (002) Subject Area Examination using the material covered in this study guide. You'll find engaging lessons on essential topics relating to body systems, cells and evolution, as well as practice quizzes to test your knowledge.
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> Frederick Douglass > What Are the Colored People Doing for Themselves?

Frederick Douglass

July 14, 1848

The present is a time when every colored man in the land should bring this important question home to his own heart. It is not enough to know that white men and women are nobly devoting themselves to our cause; we should know what is being done among ourselves. That our white friends have done, and are still doing, a great and good work for us, is a fact which ought to excite in us sentiments of the profoundest gratitude; but it must never be forgotten that when they have exerted all their energies, devised every scheme, and done all they can do in asserting our rights, proclaiming our wrongs, and rebuking our foes, their labor is lost — yea, worse than lost, unless we are found in the faithful discharge of our anti slavery duties. If there be one evil spirit among us, for the casting out of which we pray more earnestly than another, it is that lazy, mean and cowardly spirit, that robs us of all manly self-reliance, and teaches us to depend upon others for the accomplishment of that which we should achieve with our own hands. Our white friends can and are rapidly removing the barriers to our improvement, which themselves have set up; but the main work must be commenced, carried on, and concluded by our-selves. While in no circumstances should we undervalue or fail to appreciate the self-sacrificing efforts of our friends, it should never be lost sight of, that our destiny, for good or for evil, for time and for eternity, is, by an all-wise God, committed to us; and that all the helps or hindrances with which we may meet on earth, can never release us from this high and heaven-imposed responsibility. It is evident that we can be improved and elevated only just so fast and far as we shall improve and elevate our-selves. We must rise or fall, succeed or fail, by our own merits.

If we are careless and unconcerned about our own rights and interests, it is not within the power of all the earth combined to raise us from our present degraded condition.

We say the present is a time when every colored man should ask himself the question, What am I doing to elevate and improve my condition, and that of my brethren at large? While the oppressed of the old world are making efforts, by holding public meetings, putting forth addresses, passing resolutions, and in various other ways making their wishes known to the world, and the working men of our own country are pressing their cause upon popular attention, it is a shame that we, who are enduring wrongs far more grievous than any other portion of the great family of man, are comparatively idle and indifferent about our welfare. We confess, with the deepest mortification, that out of the five hundred thousand free colored people in this country, not more than two thousand can be supposed to take any special interest in measures for our own elevation; and probably not more than fifteen hundred take, read and pay for an anti-slavery paper. We say this in sorrow, not in anger. It cannot be said that we are too poor to patronize our own press to any greater extent than we now do; for in popular demonstrations of odd-fellowship, free-masonry and the like, we expend annually from ten to twelve thousand dollars. If we put forth a call for a National Convention, for the purpose of considering our wrongs, and asserting our rights, and adopting measures for our mutual elevation and the emancipation of our enslaved fellow-countrymen, we shall bring together about ; but if we call a grand celebration of odd- fellowship, or free-masonry, we shall assemble, as was the case a few days ago in New York, from — the expense of which alone would be from seventeen to twenty thousand dollars, a sum sufficient to maintain four or five efficient presses, devoted to our elevation and improvement. We should not say this of odd-fellowship and free-masonry, but that it is swallowing up the best energies of many of our best men, contenting them with the glittering follies of artificial display, and indisposing them to seek for solid and important realities. The enemies of our people see this tendency in us, and encourage it. The same persons who would puff such demonstrations in the newspapers, would mob us if we met to adopt measures for obtaining our just rights. They see our weak points, and avail themselves of them to crush us. We are imitating the inferior qualities and examples of white men, and neglecting superior ones. We do not pretend that all the members of odd-fellow societies and masonic lodges are indifferent to their rights and the means of obtaining them; for we know the fact to be otherwise. Some of the best and brightest among us are numbered with those societies; and it is on this account that we make these remarks. We desire to see these noble men expending their time, talents and strength for higher and nobler objects than any that can be attained by the weak and glittering follies of odd-fellowship and free-masonry. We speak plainly on this point, for we feel deeply. We have dedicated ourself, heart and soul, without reserve, to the elevation and improvement of our race, and have resolved to sink or swim with them. Our inmost soul is fired with a sense of the various forms of injustice to which we are daily subjected, and we must and will speak out against anything, within ourselves or our guilty oppressors, which may tend to prolong this reign of injustice. To be faithful to our oppressors, we must be faithful to ourselves; and shame on any colored man who would have us do otherwise. For this very purpose the was established — that it might be as faithful to ourselves as to our oppressors. In this respect, we intend that it shall be different from most of its predecessors, and if it cannot be sustained in its high position, its death will be welcomed by us. But to return.

It is a doctrine held by many good men, in Europe as well as in America, that every oppressed people will gain their rights just as soon as they prove themselves worthy of them; and although we may justly object to the extent to which this doctrine is carried, especially in reference to ourselves as a people, it must still be evident to all that there is a great truth in it. One of the first things necessary to prove the colored man worthy of equal freedom, is an earnest and persevering effort on his part to gain it. We deserve no earthly or heavenly blessing, for which we are unwilling to labor. For our part, we despise a freedom and equality obtained for us by others, and for which we have been unwilling to labor. A man who will not labor to gain his rights, is a man who would not, if he had them, prize and defend them. What is the use of standing a man on his feet, if, when we let him go, his head is again brought to the pavement? Look out for ourselves as we will — beg and pray to our white friends for assistance as much as we will — and that assistance may come, and come at the needed time; but unless we, the colored people of America, shall set about the work of our own regeneration and improvement, we are doomed to drag on in our present miserable and degraded condition for ages. Would that we could speak to every colored man, woman and child in the land, and, with the help of Heaven, we would thunder into their ears their duties and responsibilities, until a spirit should be roused among them, never to be lulled till the last chain is broken. — But here we are mortified to think that we are now speaking to tens where we ought to speak to thousands. Unfortunately, those who have the ear of our people on Sundays, have little sympathy with the anti-slavery cause, or the cause of progress in any of its phases. They are too frequently disposed to follow the beaten paths of their fathers. — The most they aim at, is to get to heaven when they die. They reason thus: Our fathers got along pretty well through the world without learning and without meddling with abolitionism, and we can do the same. — We have in our minds three pulpits among the colored people in the North, which have the power to produce a revolution in the condition of the colored people in this country in three years.

First among these, we may mention the great Bethel Church in Philadelphia. That church is the largest colored church in this Union, and from two to three thousand persons worship there every Sabbath. It has its branches in nearly all parts of the North and West, and a few in the South. It is surrounded by numerous little congregations in Philadelphia. Its ministers and bishops travel in all directions, and vast numbers of colored people belong to its branches all over the country. The Bethel pulpit in Philadelphia may be said to give tone to the entire denomination — “as goes large Bethel, so go the small Bethels throughout the Union.” Here is concentrated the talent of the church, and here is the central and ruling power. — Now, if that pulpit would but speak the right word — the word for progress — the word for mental culture — encourage reading, and would occasionally take up contributions to aid those who are laboring for their elevation, as the white churches do to aid the colonization society to send us out of the country — there is no telling the good that would result from such labors. An entire change might soon take place in that denomination; loftier views of truth and duty would be presented; a nobler destiny would be opened up to them, and a deeper happiness would at once be enjoyed through all the ramifications of that church.

Similarly situated is the “Zion Church” in New York. That church exerts a controlling influence over the next largest colored denomination in this country. It, too, is a unit — has its branches in all directions in the North rather than in the South. Its ministers are zealous men, and some of them powerful preachers. There is no estimating the good these men might do, if they would only encourage their congregations to take an interest in the subject of reform.

The next church in importance, is St. Phillip’s, in New York. This church is more important on account of the talent and respectability which it comprises, than for its numbers. Now, could the influence of these churches be enlisted in exciting our people to a constant and persevering effort at self-elevation, a joyful change would soon come over us.

What we, the colored people, want, is , and this nobody can give us. It is a thing we must get for ourselves. We must labor for it. It is gained by toil — hard toil. Neither the sympathy nor the generosity of our friends can give it to us. It is attainable — yes, thank God, it is attainable. “There is gold in the earth, but we must dig it” — so with character. It is attainable; but we must attain it, and attain it each for himself. I cannot for you, and you cannot for me. — What matters it to the mass of colored people of this country that they are able to point to their Peningtons, Garnets, Remonds, Wards, Purvises, Smiths, Whippers, Sandersons, and a respectable list of other men of character, which we might name, while our general ignorance makes these men exceptions to our race? Their talents can do little to give us character in the eyes of the world. We must get character for ourselves, as a people. A change in our political condition would do very little for us without this. Character is the important thing, and without it we must continue to be marked for degradation and stamped with the brand of inferiority. With character, we shall be powerful. Nothing can harm us long when we get character. — There are certain great elements of character in us which may be hated, but never despised. Industry, sobriety, honesty, combined with intelligence and a due self-respect, find them where you will, among black or white, must be — can never be . In their presence, prejudice is abashed, confused and mortified. Encountering this solid mass of living character, our vile oppressors are ground to atoms. In its presence, the sneers of a caricaturing press, the taunts of natural inferiority, the mischievous assertions of Clay, and fine-spun sophisms of Calhoun, are innoxious, powerless and unavailing. In answer to these men and the sneers of the multitude, there is nothing in the wide world half so effective as the presentation of a character precisely the opposite of all their representations. We have it in our power to convert the weapons intended for our injury into positive blessings.

That we may sustain temporary injury from gross and general misrepresentation, is most true; but the injury is but temporary, and must disappear at the approach of light, like mist from the vale. The offensive traits of character imputed to us, can only be injurious while they are true of us. For a man to say that sweet is bitter — that right is wrong — that light is darkness — is not to injure the truth, but to stamp himself a liar; and the like is true when they impute to us that of which we are not guilty. We have the power of making our enemies slanderers, and this we must do by showing ourselves worthy and respectable men. We are not insensible to the various obstacles that throng the colored man’s pathway to respectability. Embarrassments and perplexities, unknown to other men, are common to us. Though born on American soil, we have fewer privileges than aliens. The school-house, the work-shop, counting-house, attorney’s office, and various professions, are opened to them, but closed to us. This, and much more, is true. A general and withering prejudice — a malignant and active hate, pursues us even in the best parts of this country. But a few days ago, one of our best and most talented men — and he a , having lost an important limb — was furiously hurled from a car on the Niagara Buffalo Railroad, by a band of white ruffians, who claim impunity for their atrocious outrage on the plea that New York law does not protect the rights of colored against a company of white men, and the sequel has proved them right; for the case, it appears, was brought before the grand jury, but that jury found no bill. We cannot at this time dwell on this aspect of the subject.

The fact that we are limited and circumscribed, ought rather to incite us to a more vigorous and persevering use of the elevating means within our reach, than to dishearten us. The means of education, though not so free and open to us as to white persons, are nevertheless at our command to such an extent as to make education possible; and these, thank God, are increasing. Let us educate our children, even though it should us subject to a coarser and scantier diet, and disrobe us of our few fine garments. “For the want of knowledge we are killed all the day.” Get wisdom — get understanding, is a peculiarly valuable exhortation to us, and the compliance with it is our only hope in this land. — It is idle, a hollow mockery, for us to pray to God to break the oppressor’s power, while we neglect the means of knowledge which will give us the ability to break this power. — God will help us when we help ourselves. Our oppressors have divested us of many valuable blessings and facilities for improvement and elevation; but, thank heaven, they have not yet been able to take from us the privilege of being honest, industrious, sober and intelligent. We may read and understand — we may speak and write — we may expose our wrongs — we may appeal to the sense of justice yet alive in the public mind, and by an honest, upright life, we may at last wring from a reluctant public the all-important confession, that we are men, worthy men, good citizens, good Christians, and ought to be treated as such.

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